The Software Update Wizard uses the standard http protocol port for (port 80) for all its communication with the outside world. Therefore, it is fully compatible with any hardware monitoring of port 80.
As with any application's interaction with the 'outside world', you should ensure that WebUpdateSvc4.exe is authorised to communicate through any software or hardware firewalls, should these firewalls include facilities for controlling port use on a nominated application basis.
If users of your software do not have rights to set accept or deny rules for their software firewall then a rule must be separately created for the Software Update Wizard by the firewall Administrator. This is not a weakness of the Software Update Wizard - as a secure application it should not be able to violate or bypass users' firewall controls.
The Software Update Wizard populates the outgoing http header 'User-Agent' with the string "Web Update Service". This string allows http: requests from the Software Update Wizard to be specifically identified by firewalls or http: request monitoring software which is able to filter on this basis.